From the A60, take Exit 28 (Rüsselsheim Mitte, Trebur), and follow the signs for Rüsselsheim Stadtmitte. Turn right just before the traffic light onto the Kurt-Schumacher-Ring, and immediately after the ramp, exit the Kurt-Schumacher-Ring to the right and drive for 200m, following the curve. The hotel will be on your left.
The Rüsselsheim train station is located about 1.5 km from the hotel. From Frankfurt central station or airport, take S-Bahn S8 or S9 in the direction of Wiesbaden. From Mainz or Wiesbaden, take the S8 or S9 in the direction of Hanau or Offenbach. These trains also stop at the regional airport train station, on the lower floor of terminals 1 & 2. From the train station, you can come directly by taxi, or take Bus #11 to the "Kupferstraße" stop, then walk back about 300m to the hotel.